image for Mateus-Pinilla, Nohra E

Mateus-Pinilla, Nohra E

Principal Veterinary Epidemiologist

Address and Contact Information

1816 S. Oak St.
M/C 652
Champaign, IL  61820

Academic Positions

  • Clin Assoc Prof, Dept. of Animal Sciences
  • Res Assoc Prof, Dept. of Natural Resources and Environmental Sciences
  • Clin Assoc Prof, Dept. of Pathobiology


  • MBA.  (2014)
  • PhD.   (2000)  Veterinary Epidemiology & Preventive Medicine; University of Illinois Urbana-Champaign
  • MS.    (1995)  Veterinary Internal Medicine; University of Illinois Urbana-Champaign
  • DVM.  (1989)


Dr. Mateus has served as the director of the Wildlife Veterinary Epidemiology Laboratory for more than 14 years.  Regular efforts include evaluating environmental and epidemiological variables that could mitigate disease occurrence at the interface of wildlife, human and livestock health.

Her work builds on innovative multidisciplinary partnerships that expand scientific knowledge and skills in the benefit of conservation, and Ecosystem, animal and human health. She advises and co-advises undergraduate and graduate students as well as post-doctoral research associates.

Research Interests

Dr. Mateus-Pinilla is responsible for planning, developing and conducting multidisciplinary field and laboratory-oriented research. Her program builds on field, experimental and observational epidemiological studies in livestock and wildlife populations; it monitors and quantifies disease events in natural ecosystems; identifies risk factors associated with disease occurrence, persistence and transmission; and evaluates the impact of diseases in the conservation and preservation of species.

Her research applies epidemiological theory to multiple species in natural systems. It thrives to understand the impact of diseases in populations and the role of natural levels of biodiversity in mediating the persistence of pathogens in the environment.  Her program guides applied adaptive management strategies that take into account restoration, conservation and ecosystem health at the interface of conservation, wildlife-livestock and human health.

Selected Publications


Knowledge, attitudes, and practices of Illinois medical professionals related to ticks and tick-borne disease. One Health. 2022 Jul 31:100424. Carson DA, Kopsco H, Gronemeyer P, Mateus-Pinilla N, Smith GS, Sandstrom EN, Smith RL.

Effects of tick surveillance education on knowledge, attitudes, and practices of local health department employees. BMC public health. 2022 Dec;22(1):1-5. Lyons LA, Mateus-Pinilla N, Smith RL.

Knowledge, attitudes, and practices of veterinary professionals towards ticks and tick-borne diseases in Illinois. One Health. 2022 Jun 1;14:100391. Crist SD, Kopsco H, Miller A, Gronemeyer P, Mateus-Pinilla N, Smith RL.

A De Novo Chromosome-level Genome Assembly of the White-tailed Deer, Odocoileus virginianus. Journal of Heredity. 2022 May 3.  London EW, Roca AL, Novakofski JE, Mateus-Pinilla NE.

Spatial epidemiology of hemorrhagic disease in Illinois wild white-tailed deer. Scientific reports. 2022 Apr 27;12(1):1-2.  Dorak SJ, Varga C, Ruder MG, Gronemeyer P, Rivera NA, Dufford DR, Skinner DJ, Roca AL, Novakofski J, Mateus-Pinilla NE.

Variation in the PRNP gene of Pere David’s deer (Elaphurus davidianus) may impact genetic vulnerability to chronic wasting disease.  Perrin-Stowe TI, Ishida Y, Terrill EE, Beetem D, Ryder OA, Novakofski JE, Mateus-Pinilla NE, Roca AL. Conservation Genetics. 2022 Apr;23(2):313-23.

Effects of Climate on the Variation in Abundance of Three Tick Species in Illinois. Journal of medical entomology. 2022 Mar;59(2):700-9. Bacon EA, Kopsco H, Gronemeyer P, Mateus-Pinilla N, Smith RL.


Evaluating the ability of a locally focused culling program in removing chronic wasting disease infected free‐ranging white‐tailed deer in Illinois, USA, 2003–2020.  Varga C, McDonald P, Brown WM, Shelton P, Roca AL, Novakofski JE, Mateus‐Pinilla NE.  Transboundary and Emerging Diseases. 2021 Dec.

Bluetongue and Epizootic Hemorrhagic Disease in the United States of America at the Wildlife–Livestock Interface. Pathogens. 2021 Aug;10(8):915.  Rivera NA, Varga C, Ruder MG, Dorak SJ, Roca AL, Novakofski JE, Mateus-Pinilla NE.

Comparing contributions of passive and active tick collection methods to determine establishment of ticks of public health concern within Illinois. Journal of medical entomology. 2021 Jul;58(4):1849-64.  Lyons LA, Brand ME, Gronemeyer P, Mateus-Pinilla N, Ruiz MO, Stone CM, Tuten HC, Smith RL.

Spatial analysis of chronic wasting disease in free‐ranging white‐tailed deer (Odocoileus virginianus) in Illinois, 2008–2019. Transboundary and Emerging Diseases. 2021 Jul;68(4):2376-83.  Hedman HD, Varga C, Brown WM, Shelton P, Roca AL, Novakofski JE, Mateus‐Pinilla NE.

A survey of tick surveillance and control practices in the United States.  Journal of medical entomology. 2021 Jul;58(4):1503-12.  Mader EM, Ganser C, Geiger A, Harrington LC, Foley J, Smith RL, Mateus-Pinilla N, Teel PD, Eisen RJ.

Preliminary Study of Cave Sample Storage Conditions on Fungal Community Diversity. Diversity. 2021 May;13(5):188. Raudabaugh DB, Rivera NA, Anchor GC, Bach E, Miller AN, Mateus-Pinilla NE.


Hedman, HD., Varga, C., Duquette, J., Novakofski, J. and Mateus-Pinilla, NE., 2020. Food Safety Considerations Related to the Consumption and Handling of Game Meat in North America. Veterinary Sciences, 7(4), p.188. 


Perrin-Stowe TI, Ishida Y, Terrill EE, Hamlin BC, Penfold L, Cusack LM, Novakofski J, Mateus-Pinilla NE, Roca AL. 2020. Prion protein gene (PRNP) sequences suggest differing vulnerability to chronic wasting disease for Florida Key deer (Odocoileus virginianus clavium) and Columbian white-tailed deer (O. v. leucurus). Journal of Heredity. esaa040

Gilliam B, Gronemeyer P, Chakraborty S, Winata F, Lyons LA, Miller-Hunt C, Tuten HC, Debosik S, Freeman D, O’Hara-Ruiz M, Mateus-Pinilla N. 2020. Impact of unexplored data sources on the historical distribution of three vector tick species in Illinois. Journal of medical entomology57(3), pp.872-883. [pdf]

Ishida Y, Tian T, Brandt AL, Kelly AC, Shelton P, Roca AL, Novakofski J, Mateus-Pinilla NE. 2020. Association of chronic wasting disease susceptibility with prion protein variation in white-tailed deer (Odocoileus virginianus). Prion14(1), pp.214-225. [pdf]

Grimm K, Rivera NA, Fredebaugh-Siller S, Weng HY, Warner RE, Maddox CW, Mateus-Pinilla NE. 2020. Evidence of Leptospira serovars in wildlife and leptospiral DNA in water sources in a natural area in East-Central Illinois, USA. Journal of Wildlife Diseases. October 2019; 56(2) 2020, pp. 316-327 [pdf]


Gilliam B., Gronemeyer P., Chakraborty S., Winata F., Lyons L.A., Miller-Hunt C., Tuten H.C., Debosik S., Freeman D., O’hara-Ruiz M., Mateus-Pinilla NE. 2019. Impact of Unexplored Data Sources on the Historical Distribution of Three Vector Tick Species in Illinois. Journal of Medical Entomology. December 2019; 1—12.

Rivera NA, Brandt AL, Novakofski JE, Mateus-Pinilla NE. 2019. Chronic Wasting Disease in Cervids: Prevalence, Impact and Management Strategies. Veterinary Medicine: Research and Reports. October 2019; 10:123—139. [Full Text]

Trone‐Launer EK, Wang J, Lu G, Mateus‐Pinilla NE, Zick PR, Lamer JT, Shelton PA, Jacques CN. 2019. Differential gene expression in chronic wasting disease‐positive white‐tailed deer (Odocoileus virginianus). Ecology and Evolution, 9(22), pp.12600-12612 [pdf].

Wang L, Lanka S, Cassout D, Mateus‐Pinilla NE, Li G, Wilson WC, Yoo D, Shelton P, Fredrickson RL. 2019. Inter‐serotype reassortment among epizootic haemorrhagic disease viruses in the United States. Transboundary and emerging diseases. 2019 Sep;66(5):1809-20 [pdf].


Rivera NA, Totoni S, Monick K., Tian T, Green ML, Novakofski J, Mateus-Pinilla NE. 2018. A comparison of three methods to evaluate otter latrine activity. Wildlife Society Bulletin. Accepted December 2018. [pdf]

Brandt AL, Green ML, Ishida Y, Roca AL, Novakofski J, Mateus-Pinilla NE. 2018. Influence of the geographic distribution of prion protein gene sequence variation on patterns of chronic wasting disease spread in white-tailed deer (Odocoileus virginianus). Prion, July 22:1-2. [pdf]


Dorak SJ, Green ML, Wander MM, Ruiz MO, Buhnerkempe MG, Tian T, Novakofski JE, Mateus-Pinilla, NE. 2017. Clay content and pH: soil characteristic associations with the persistent presence of chronic wasting disease in northern Illinois. Scientific Reports, 7(1), p.18062. [pdf]

Annetti KL, Rivera NA, Andrews JE, Mateus-Pinilla NE. 2017. Survey of haemosporidian parasites in resident and migrant game birds of Illinois. Journal of Fish and Wildlife Management. 8(2): 661-668. [pdf]

Green ML, Kelly A, Satterthwaite-Phillips D, Manjerovic MB, Shelton P, Novakofski J, Mateus-Pinilla NE. 2017. Reproductive characteristics of female white-tailed deer (Odocoileus virginianus) in the Midwestern USA. Theriogenology, 94: 71-78 [pdf]


Brandt AL, Kelly AC, Green ML, Shelton P, Novakofski J, Mateus-Pinilla NE. 2015. Prion Protein gene sequence and chronic wasting disease susceptibility in white-tailed deer (Odocoileus virginianus). Prion, 9(6): 449-462 [pdf]

Rivera NA, Mateus-Pinilla NE, Novakofski J, Satterthwaite-Phillips D. 2015. Metals in obex and retropharyngeal lymph nodes of Illinois white-Tailed deer and their variations with sex and CWD status. Prion, 9 (1): 48-58 [pdf]

Green ML, Monick K, Manjerovic MB, Novakofski J, Mateus-Pinilla NE. 2015. Communication stations: cameras reveal river otter (Lontra canadensis) behavior and activity patterns at latrines. Journal of Ethology, 33 (3): 225-234 [pdf]

Manjerovic MB, Green ML, Mateus-Pinilla NE, Miller AN, Novakofski J. 2015. Trash to treasure: assessing viability of wing biopsies for use in bat genetic research. Conservation Genetic Resources, 7 (2): 325-327 [pdf]


Green ML, Novakofski J, Green RW, Manjerovic MB, Mateus-Pinilla NE. 2014. The scene of the crime: classroom integration of biosafety, microscopy and forensics. The American Biology Teacher, 76(9): 615-619

Satterthwaite-Phillips D, Mateus-Pinilla NE, Novakofski J. 2014. Fatty acid analysis as a tool to infer the diet in Illinois River otters (Lontra canadensis). Journal of Animal Science and Technology 56 (1): 1-9 [pdf]

Green ML, Manjerovic MB, Mateus-Pinilla NE, Novakofski J. 2014. Genetic assignment tests reveal dispersal of white-tailed deer: implications for chronic wasting disease. Journal of Mammalogy, 95(3): 646-654 [pdf]

Kelly AC, Mateus-Pinilla NE, Brown, W, Ruiz MO, Douglas M, Douglas M, Shelton P, Beissel T, Novakofski J. 2014. Genetic Assessment of Environmental Features that Influence Deer Dispersal: Implications for Prion Infected Populations. Population Ecology. 56:327-340 [pdf]

Manjerovic MB, Green ML, Mateus-Pinilla NE, Novakofski J. 2014. The importance of localized culling in stabilizing chronic wasting disease prevalence in white-tailed deer populations. Preventive Veterinary Medicine, 113(1): 139-145 [pdf]

Carpenter SK, Mateus-Pinilla NE, Singh K, Lehner A, Satterthwaite-Phillips D, Bluett RD, Rivera NA, Novakofski JE. 2014. River otters as biomonitors for organochlorine pesticides, PCBs, and PBDEs in Illinois. Ecotoxicology and Environmental Safety 100, 99-104 [pdf]


O’Hara Ruiz M, Kelly AC, Brown WM, Novakofski J, Mateus-Pinilla NE. 2013. Influence of landscape factors and management decisions on spatial and temporal patterns of the transmission of chronic wasting disease in white-tailed deer. Geospatial Health 8(1), 215-227 [pdf]

Green ML, Ting T-F, Manjerovic MB, Mateus-Pinilla NE, Novakofski J. 2013. Noninvasive alternatives for DNA collection from threatened rodents. Natural Science, 5(5A), 18-26 [pdf]

Mateus-Pinilla NE, Weng HY, Ruiz MO, Shelton P, Novakofski J. 2013. Evaluation of a wild white-tailed deer population management program for controlling chronic wasting disease in Illinois, 2003-2008. Preventative Veterinary Medicine. DOI:10.1016 [pdf]

Awobode HO, Paul AJ, Sengoku-Graham H, Clem RW, Mateus-Pinilla NE, McAllister MM. 2013. Serial Monoxenous Transmission of Toxoplasma gondii in cats. Journal of Parasitology 99(6): 1122-1124


Green ML, Manjerovic MB, Mateus-Pinilla NE, Kelly AC, Shelton PA, Novakofski J. 2012. Determining source populations of newly identified cases of chronic wasting disease in white-tailed deer. FASEB Journal. March 29, 2012 26:1035.6

Manjerovic MB, Green ML, Kelly AC, Mateus-Pinilla NE, Shelton P, Novakofski J. 2012. Spatial variation in susceptibility to chronic wasting disease in white-tailed deer. FASEB Journal March 29, 2012 26:1035.5

Rydzewski J, Mateus-Pinilla NE, Warner RE, Nelson JA, Velat TC. 2012Ixodes scapularis (Acari: Ixodidae) distribution surveys in the Chicago metropolitan region. Journal of Medical Entomology. 49(4):955-9


Kmieciak LA, Mateus-Pinilla NE, Novakofski J. 2011. Developing a panel of microsatellites to determine genetic relatedness with white-tailed deer. FASEB Journal March 17, 2011 25:793.10

Kelly AC, Mateus-Pinilla NE, Douglas M, Douglas M, Shelton P, Novakofski J. 2011. Microsatellites behaving badly: empirical evaluation of genotyping errors and subsequent impacts on population studies. Genetics and Molecular Research. 10(4): 2534-2553 [pdf]

Fredebaugh SL, Mateus-Pinilla NE, McAllister M, Warner RE, Weng H. 2011. Prevalence of antibody toToxoplasma gondii in terrestrial wildlife in a natural area. Journal of Wildlife Diseases. 47(2):381-92 [pdf]

Horn JA, Mateus-Pinilla NE, Warner RE, Heske EJ. 2011. Home range, habitat use, and activity patterns of free-roaming domestic cats. Journal of Wildlife Management. 75(5): 1177-1185

Rydzweski J, Mateus-Pinilla N, Warner RE, Hamer S, Weng H. 2011. Ixodes scapularis and Borrelia burgdorferiamong diverse habitats within a natural area in east-cental Illinois. Vector-borne and Zoonotic Diseases. 11(10) :1351-1358

» Email Karen Ballen at Vector-borne and Zoonotic Diseases for a copy []


Kelly AC, Mateus-Pinilla NE, Douglas M, Douglas M, Brown W, Ruiz MO, Killefer J, Shelton P, Beissel T, Novakofski J. 2010. Utilizing disease surveillance to examine gene flow and dispersal in white-tailed deer. Journal of Applied Ecology. 47(6): 1189-1198 [pdf]

Lehrer EW, Fredebaugh SL, Schooley RL, Mateus-Pinilla NE. 2010. Prevalence of antibodies to Toxoplasma gondii in woodchucks across an urban-rural gradient. Journal of Wildlife Disease. 46(3): 977-980 [pdf]


Kelly A,  Mateus-Pinilla NE, Emily J, Diffendorfer J, Killefer J, Shelton P, Beissel T, Novakofski J.  2008.  Prion sequence polymorphisms and Chronic Wasting Disease resistance in Illinois White-tailed Deer (Odocoileus virginianus), Prion 2(1): 28-36  [pdf]


Bahnson PB,  Fedorka-Cray PJ,  Ladely SR, Mateus-Pinilla NE2006Herd-level risk factors for Salmonella enterica subsp. enterica culture prevalence in U.S. market pigs. Journal of Veterinary Preventive Medicine.  76:249-262

Bunde JM, Heske EJ, Mateus-Pinilla NE, Hofmann JE, Novak R. 2006A Survey for West Nile Virus in Bats from Illinois. Journal of Wildlife Diseases  42(2): 455-458 [pdf]


Novakofski J, Brewer MS, Mateus-Pinilla NE, Killefer J, McCusker Jr R. 2005.  Prion Biology Relevant to BSE. Journal of Animal Science 83:1455-1476


Gondim LFP, McAllister MM, Mateus-Pinilla NE, Pitt WC, Mech LD, Nelson ME.  2004.Transmission of Neospora caninum between wild and domestic animals. Journal of Parasitology 90 (6):1361-1365


Regula G, Scherba G, Mateus-Pinilla NE, Lichtenstiger CA, Miller GY, Weigel RM.  2003The impact of endemic porcine reproductive and respiratory syndrome virus and other pathogens on reproductive performance in swine. Journal of Swine Health and Production.  11(1):13-18 [pdf]


Mateus-Pinilla NE , Hannon B, Weigel RM. 2002A computer simulation of the prevention of the transmission of Toxoplasma gondii on swine farms using a feline T. gondii vaccine. Preventive Veterinary Medicine 55(1):17-36


Cope RB, Miller CA, Post M, Mateus-Pinilla NE, Murphy JE, Beasley VR. 2000Use of synthetic human luteinizing hormone releasing hormone for induction of breeding in the cricket frog, Acris crepitans. Journal of Herpetological Medicine and Surgery Volume 10(1):7-8 [pdf]

Regula G, Lichtensteiger CA, Mateus-Pinilla NE, Scherba G, Miller GY, Weigel RM. 2000Comparison of serologic testing and slaughter evaluation for assessing the effects of subclinical infection on growth in pigs. Journal of the American Veterinary Medical Association. 217: 888-895


Mateus-Pinilla NE, Dubey JP,  Choromanski L, and Weigel RM. 1999A Field Trial on the Effectiveness of a Feline Toxoplasma Gondii Vaccine in Reducing T. Gondii  Exposure for Swine.  Journal of Parasitology 85(5):855-860

Regula G, Lichtensteiger CA, Mateus-Pinilla NE, Miller GY, Scherba G, Weigel  RM, Goodall EA, Thrusfield MV.  1999. Monitoring the impact of subclinical infection on performance by serological testing and slaughter evaluation. Society for Veterinary Epidemiology and Preventive Medicine. Proceedings of a meeting held at the University of Bristol, UK, on the 24-26th March, 1999:110-117


Mateus-Pinilla NE, Weigel RM, Dubey JP.  1997A Field Trial on the Effectiveness of a Feline Toxoplasma Vaccine in Reducing Toxoplasma Exposure for Swine.  VIII International Symposium on Veterinary Epidemiology and Economics (ISVEE), Epidemiologie-et-Sante-Animale, Vol. 1:  04.14.1-04.14.3 [pdf]

Regula G,  Mateus-Pinilla NE,  Lichtensteiger CA, Scherba G, Miller GY,  Weigel RM. 1997. Development and evaluation of a swine herd health monitoring system. Epidemiologie-et-Sante-Animale, No. 31-32, 07.B.34 [pdf]


Dubey JP, Weigel RM, Siegel AM, Thulliez P, Kitron UD, Mitchell MA, Mannelli AM, Mateus-Pinilla NE,  Shen SK, Kwok O, Todd KS. 1995Sources and Reservoirs of Toxoplasma gondii Infection on 47 Swine Farms in Illinois. J. Parasitol.  81(5):723-729

Weigel RM, Dubey JP, Siegel AM, Kitron UD, Mannelli AM, Mitchell  MA, Mateus-Pinilla NE,Thulliez P, Shen K, Kwok O, Todd, KS. 1995.  Risk Factors for Transmission of Toxoplasma gondii on Swine Farms in Illinois.  J. Parasitol. 81(5):736-741

Mateus-Pinilla NE. 1995. Theophylline effects on canine PMN phagocytosis as measured in whole blood by luminol-dependent chemiluminescence. Doctoral Thesis.

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